Researchers from the Health Research Institute of the Hospital Clínico de Valencia (INCLIVA) have shown that a molecule used to treat cancer, called PD033299, increases the number of a type of protective cells known as T cells of the cholesterol plate. , which makes it more resistant to artery ruptures, so that “the most serious cases of atherosclerosis could be improved”.
Atherosclerosis occurs when cholesterol and inflammatory cells accumulate in the walls of the arteries. These deposits, which are called plaques, can narrow or clog the arteries and break them over time. In patients with this pathology in severe phase the risk of suffering a cardiovascular accident is very high.
The results of the investigation of INCLIVA showed “that the treatment with the molecule PD0332991 increases the amount of these protective T cells and reduces cardiovascular disease and vulnerability to plaque rupture in animal models”, as reported by the Government of the Valencian Community .
The authors consider that therapeutic routes based on the activation of these genes “could be a possible treatment for those patients at high risk of suffering a cardiovascular event. For this, it will be necessary to carry out more studies, not only in the laboratory, but also with patients “, adds the Generalitat Valenciana.
At Distefar we encourage you to continue researching these cells that could improve the most severe cases of atherosclerosis.